Jack3d Advanced Formula

Jack3d Advanced Formula Review

Since its introduction, Jack3d has consistently impressed athletes and bodybuilders with its ability to create energy and support hardcore workouts. Now, USPLabs is introducing Jack3d Advanced.

What’s Different About Jack3d Advanced?

USPLabs has many products in the Jack3d line already, so why make Jack3d Advanced?

If you’ve been following USPLabs or even the supplement industry in general, you know the U.S. Food and Drug Administration issued a warning against products containing 1,3 dimethylamylamine (DMAA) in August 2012. In April 2013, the FDA banned DMAA altogether.

Unfortunately for USPLabs, DMAA was the active ingredient in the original Jack3d formula. Until April, USPLabs fought FDA opposition to the stimulant and continued to market Jack3d. However, in the eventuality DMAA was banned outright, USPLabs introduced an alternative—Jack3d Micro.

Jack3d Micro has been on the market for close to a year, but has failed to catch on with the original Jack3d audiences. Now USPLabs is trying again with Jack3d Advanced.

Jack3d Advanced doesn’t contain DMAA. I decided to look at the ingredients.

What Ingredients Are in Jack3d Advanced?

The ingredients in Jack3d Advanced are listed in a 3580 mg proprietary blend. While all the ingredients are listed, individual ingredient doses are not, which makes it hard to know each ingredient’s effectiveness.

Advanced Creatine Ratio (Monohydrate, Anhydrous). This formula mixes 2 creatine forms to optimize ATP levels for greater energy during exercise. Medical authorities believe creatine monohydrate bioavailability is close to 100%. [1] I wasn’t able to find any clinical studies involving creatine anhydrous specifically, but the manufacturer claims it is the purest form of creatine.

Creatine is clinically proven to enhance strength and athletic performance.

In one study, 36 collegiate volleyball players were commited to train 3 times a week and were either given 5 g creatine a day or a placebo. Research revealed the creatine group experienced significantly higher increases in bench press and vertical jump than the placebo group. [2]

Arginine Nitrate. Arginine is said to expand blood vessels by converting into nitric oxide. As a result, arginine optimizes blood flow throughout the body. Also, when arginine is combined with antioxidants (like pinus pinaster) it is said to enhance anaerobic activity. [3]

Arginine nitrate also yields the nitrate ion, utilizing the nitrate-nitrite-nitric oxide pathway, a recently discovered pathway, which can generate an increase in nitric oxide through several other routes. [4]

Pinus Pinaster (Bark) Extract. The National Institutes of Health claims pinus pinaster improves blood flow. [5] Also, it is clinically proven to reduce pain and muscle cramps during training.

Researchers administered 200 mg pinus pinaster extract per day for 5 weeks to 66 healthy subjects and then observed muscle cramp attacks. Patients experienced statistically significant muscle pain and cramps than they did without the supplement. [6]

Beta Alanine (Carnosyn). Carnosyn is a patented beta-alanine form. Beta-alanine is a naturally occurring beta amino acid and is a major contributor to carnosine. Carnosine regulates acid-base balance in the body, mediates lactic acid levels, and optimizes high-intensity training capacity. [7]

Thirteen males participated in isometric endurance tests for 4 weeks and were given either a placebo or 6.4 g beta-alanine daily. Subjects completed isometric knee tests before and after beta-alanine supplementation. The subjects experienced an increase in endurance capacity of the knee extensors, which researchers attributed to “improved pH regulation within the muscle cell as a result of elevated muscle carnosine levels. [8]

Yohimbe Extract. Yohimbe extract, often used to combat sexual dysfunction, increases peripheral blood flow. [9] Though, how much is needed to enhance blood flow is not available. Additionally, how much is included in Jack3d Advanced Formula is unknown.

Norcoclaurine HCL. Also known as higenamine, norcoclaurine HCL is thought to improve blood flow as well, though, there are insufficient clinical studies supporting these claims.

Swertia Chirayita (Whole Plant) Extract. This plant purportedly stimulates central nervous system activity. However, there is insufficient evidence to support these claims.

Caffeine (100 mg). Caffeine is a stimulant responsible for various metabolic effects, such as increased physical and mental energy. [10] Caffeine is clinically proven to enhance resistance training.

Researchers administered 5 mg/kg caffeine to 18 male athletes before intense resistance training. Research reveals caffeine supplementation “resulted in more total weight lifted for the chest press and a greater peak power.” [11]

Depending on how much users weigh, the caffeine amount in Jack3d Advanced Formula should produce similar effects.

Side Effects

Due to its recent release, Jack3d Advanced Formula side effects are unknown. However, there are some side effects associated with the ingredients in Jack3d Advanced Formula. These side effects include restlessness, nausea, increased heart rate, kidney failure, heart attack, diarrhea, low blood pressure, abdominal pain, and bloating. [12] [13] [14] [15]

Recommended Use

Mix 1 Ultra-Concentrated Scoop (5.1 grams) with 4 ounces of cold water and consume 30-45 minutes prior to resistance training. Do this the first 3 times using the product. Beginning with the 4th use, if needed, you may gradually increase serving by a half scoop (2.55 grams), up to a total of 2 full scoops.

It is not recommended to exceed 2 full scoops or use more than 5 days in a 7 day period. The manufacturer also recommends drinking at least 125 fl. oz. liquid per day for men and 91 fl. oz. liquid per day for women.

What About the Original Jack3d?

Jack3d, as well as USPLabs’ OxyElite Pro, will both continue to be sold despite the FDA ban. However, the products are officially discontinued, which means the existing supply is all USPLabs has left to sell.

If you’re a fan of the original Jack3d formula, you’d better snap up the few remaining bottles while you can. As the administrator expects Jack3d to be sold out by August or September, you’ll want to stock up fast.

How Much Is Jack3d Advanced Formula?

For a promotional introductory price, Jack3d Advanced Formula can be purchased for $19.99 with FREE USPS Priority Mail Shipping from USPLabsDirect.com.

Is Jack3d Advanced Formula a Great Product?

Ingredients in Jack3d Advanced Formula are clinically proven (with the exception of norcoclaurine HCL and swertia chirayita) to increase blood flow, optimize physical performance, and combat fatigue. Though, not including specific doses for each ingredient is a disadvantage for the user.

The Jack3d Advanced Formula starter-price is pretty inexpensive, so if you are interested, I suggest acting now before the prices go up.


[1] Ralf Jager, Roger C Harris, […] and Marc Francaux. “Comparison of new forms of creatine in raising plasma creatine levels.” J Int Soc Sports Nutr. 2007; 4:17. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206055/

[2] Jon YeanSub Lim. “Effects of Creatine Supplementation on Body Compositon, Strength, and Power of Female Volleyball Players.” Abstract. United States Sports Academy. The Sport Journal. Available from: http://www.thesportjournal.org/article/effects-creatine-supplementation-body-composition

[3] Steven Chen et al. “Arginine and antioxidant supplement on performance in elderly male cyclists: a randomized controlled trial.” J Int Soc Sports Nutr. 2010, 7:13. doi:10.1186/1550-2783-7-13. Available from: http://www.jissn.com/content/7/1/13

[4] Lundberg JO, Weitzberg E, Gladwin MT. “The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics.” Nat Rev Drug Discov. 2008 Feb;7(2):156-67. Doi: 10.1038/nrd2466. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18167491

[5] “Pycnogenol.” MedlinePlus. Available from: http://www.nlm.nih.gov/medlineplus/druginfo/natural/1019.html

[6] Vinciguerra G et al. “Cramps and muscular pain: prevention with pycnogenol in normal subjects, venous patients, athletes, claudicants and in diabetic microangiopathy.” Angiology. 2006 May-Jun;57(3):331-9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16703193

[7] Suzuki Y, Ito O, Mukai N, Takahashi H, Takamatsu K. “High level of skeletal muscle carnosine contributes to the latter half of exercise performance during 30-s maximal cycle ergometer sprinting.” Jpn J Physiol. 2002 Apr;52(2):199-205. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12139778

[8] Craig Sale, Chester A Hill, […], and Roger C Harris. “Beta-alanine supplementation improves isometric endurance of the knee extensor muscles.” J Int Soc Sports Nutr. 2012; 9;26. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420321/

[9] “Yohimbine (Oral Route).” Mayo Clinic. Available from: http://www.mayoclinic.com/health/drug-information/DR601453

[10] “Ask the Professor.” Tufts Journal. March 18, 2009. Available from: http://tuftsjournal.tufts.edu/2009/03_2/professor/01/

[11]Woolf K, Bidwell WK, Carlson AG. “The effect of caffeine as an ergogenic aid in anaerobic exercise.” Int J Sport Nutr Exerc Metab. 2008 Aug;18(4):412-29. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18708685

[12] “Caffeine.” WebMD Available from: http://www.webmd.com/vitamins-supplements/ingredientmono-979-CAFFEINE.aspx?activeIngredientId=979&activeIngredientName=CAFFEINE

[13] ”Yohimbe.” WebMD Available from: http://www.webmd.com/vitamins-supplements/ingredientmono-759-YOHIMBE.aspx?activeIngredientId=759&activeIngredientName=YOHIMBE

[14] “Arginine.” WebMD Available from: http://www.webmd.com/vitamins-supplements/ingredientmono-875-arginine.aspx?activeIngredientId=875&activeIngredientName=arginine&source=1

[15] “Creatine.” WebMD Available from: http://www.webmd.com/vitamins-supplements/ingredientmono-873-creatine.aspx?activeIngredientId=873&activeIngredientName=creatine&source=1

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